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Immunoglobulin G (IgG) antibodies from FM subjects, when transferred into mice, induced FM-like symptoms 7 such as heightened sensitivity to painful stimuli and reduced intraepidermal nerve fiber density (IENFD), consistent with previous observations in FM patients 8

doi: 10.1016/0042-6822(91)90893-G 22 RickinsonA

Table 5 *VMM, variants being monitored

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